Walking again after ten years with Multiple Sclerosis

This is really fantastic news and happy to find out that someone who was with Multiple Sclerosis was able to get back on his legs after ten years.

The recent research and development on Relapsing Multiple sclerosis has opened up new frontiers. Roy Palmer, 49 was diagnosed with Multiple Sclerosis ten years back. He and his doctor decided to go for HSCT (Hematopoietic stem cell transplantation) in the United Kingdom.

During the HSCT the patient’s stem cell is removed, frozen and stored. While this is being done. Removing a healthy stem cell is done from our own spinal cord, or if you have healthy sibling or going for a donor of stem cell.

Roy Palmer stem cell was harvested from the spinal cord and had to go through several rounds of Chemotherapy. This is done to bring down your immune system and to kill the unhealthy cells.

Precaution need to taken while your immune system is down, since even a small infection can prove to be fatal. Once the chemotherapy session is done, the healthy stem cell is transplanted again back to our human body.

HSCT (Hematopoietic stem cell transplantation) has proved to be very effective in case of Roy Palmer as today he is able to walk without any support.

The whole Multiple Sclerosis group and foundation is very happy on this break through treatment.

Does Avonex suppress the immune system and bring down your hemoglobin levels?

Avonex claims that it is not an immunity suppressant and it is an immunity modulator. But while you are on a long time therapy of Avonex beta interferons it brings down the immunity and infection fighting capability of the patient.

The most common infection Multiple Sclerosis patients suffer is Urinary tract infection due to less immunity. Bacteria thrives in the Urinary track and affects the bladder. Suppressed immunity creates less hemoglobin levels and RBC count. This leads to iron deficiency among the Multiple Sclerosis patients.

It is very much important to do the urine and blood routine among the MS patients. Also it is a good health check to get the liver function test (LFT) and  test among the  Serum glutamic pyruvic transaminase (SGPT) test among the MS patients to fing out if there has been a damage done on long time therapy of Avonex beta interferon injections.

Dalfampridine for Multiple Sclerosis

Dalfampridine is a drug used to improve imbalance and walking among multiple sclerosis.

Ampyra was the first approved branded oral tablet for Dalfampridine. Now recently from 2018 onwards USFDA approved Dalstep Dalfampridine 10mg extended release tablets are available from Sun Pharmaceuticals Pvt Ltd.

What is Dalfampridine?

Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients to improve body imbalance and help in walking.

How does Dalfampridine work?

In multiple sclerosis the nerves are progressively demyelinated which exposes potassium channels. Due to this there is a leak of potassium which results in distortion of signals throughout the nerves. This results delay in signals and impairment of neuromuscular transmission.

Dalfampridine inhibits voltage-gated potassium channels in the Central Nerves System to maintain the transmembrane potential and prolong action potential. In simple language, dalfampridine works to make sure that the signal available is high enough to stimulate conduction in demyelinated nerves that are exposed in MS patients.

Is there a generic drug for Ampyra?

Yes, USFDA approved Dalstep Dalfampridine 10mg Extended Release tablets are now available as generic drug for Ampyra.

Dalfampridine Generic Drug Dalstep 10mg